Vitalii Mandziuk is a trainee of the Simferopol School of the Olympic Reserve. He started his professional career in "Dynamo" Kyiv. He played 22 matches for Kyiv. He mainly played for farm clubs - "Dynamo-3" and "Dynamo-2", for which he played a total of 62 games and scored 3 goals. He spent the first half of the 2008/09 season on loan at Kyiv's "Arsenal". With "Dynamo" he twice became the champion of Ukraine (2006/07, 2008/09), the winner of the Cup of Ukraine (2006/07) and the Super Cup of Ukraine (2007).
On December 23, 2009, it was decided to transfer Mandziuk to "Dnipro". He was the team captain. In total, "Dnipro" played 95 matches in a T-shirt, in which he scored 2 goals. On October 16, 2017, live on the TV channel "Football 1" announced the end of his career due to a chronic leg injury.
He made his national team debut on February 6, 2008 in a friendly match against Cyprus. As a result, he played 24 matches for the main team of the country and scored 1 goal.
Since the spring of 2020, he has been responsible for the physical training and rehabilitation of football players in "Kolos".
Achievements:
Champion of Ukraine: 2006/07, 2008/09
Winner of the Cup of Ukraine: 2006/07
Winner of the Super Cup of Ukraine: 2007